Cytokine-Related Aging Process

[The aging process].

Aging-related Genes

Genetic factors affect an individual’s maximum possible lifespan. In humans, the average lifespan is about 40 years shorter than the maximum lifespan. Any gene that influences the development of a disease is called a disease-susceptibility gene. The impacts of disease-susceptibility genes on aging and average lifespan would be much stronger than the impacts of aging genes on maximum lifespan. M...

[Adrenocortical hormones and aging process].

Concerning the adrenocortical hormones and the aging process, especially in childhood and adolescence, the results by age level of the studies bythe author and coworkers on the following items are summarized : 1) Plasma levels of cortisol and corticosterone, 2) Plasma transcortin binding of C-14 cortisol (% bound) and erythrocyte C-14 cortisol uptake, 3) Plasma cortisol levels after ACTH stimul...

Hormones and the Aging Process

tion of samples and normal values. Part two is devoted to methods of analysis of biological fluids. The description of each method includes an introduction, recommended procedure or procedures, discussion, brief note on the physiological significance, and bibliography. The subject matter is treated in a simple and direct way, which is by no means complete, but the material is well selected to b...

Senescence in the aging process

The accumulation of 'senescent' cells has long been proposed to act as an ageing mechanism. These cells display a radically altered transcriptome and degenerative phenotype compared with their growing counterparts. Tremendous progress has been made in recent years both in understanding the molecular mechanisms controlling entry into the senescent state and in the direct demonstration that senes...